Publications

16. Genetic predisposition to increased serum calcium, bone mineral density, and fracture risk in individuals with normal calcium levels: mendelian randomisation study. Cerani A, Zhou S, Forgetta V, Morris JA, Trajanoska K, Rivadeneira F, Larsson SC, Michaëlsson K, Richards JB. The British Medical Journal (2019).

15. An atlas of genetic influences on osteoporosis in humans and mice. Morris JA*, Kemp JP*, Youlten SE, Laurent L, Logan JG, Chai RC, Vulpescu NA, Forgetta V, Kleinman A, Mohanty ST, Sergio CM, Quinn J, Nguyen-Yamamoto L, Luco A-L, Vijay J, Simon M-M, Pramatarova A, Medina-Gomez C, Trajanoska K, Ghirardello EJ, Butterfield NC, Curry KF, Leitch VD, Sparkes PC, Adoum A-T, Mannan NS, Komla-Ebri D, Pollard AS, Dewhurst HF, Hassall TAD, Beltejar M-JG, 23andMe Research Team, Adams DoJ, Vaillancourt SM, Kaptoge S, Baldock P, Cooper C, Reeve J, Ntzani E, Evangelou E, Ohlsson C, Karasik D, Rivadeneira F, Kiel DP, Tobias JH, Gregson CL, Harvey NC, Grundberg E, Adams DaJ, Lelliott CJ, Hinds DA, Ackert-Bicknell CL, Hsu Y-H, Maurano MT, Croucher PI, Williams GR, Bassett JHD, Evans DM, Richards JB. Nature Genetics (2018).

14. Assessment of the genetic and clinical determinants of fracture risk: Genome-wide association and Mendelian randomization study.Trajanoska K*, Morris JA*, Oei L*, Zheng H-F*, Evans DM, Kiel DP, Ohlsson C, Richards JB and Rivadeneira F; on behalf of the GEFOS/GENOMOS Consortium and the 23andMe Research Team. The British Medical Journal (2018).

13. Genome-wide association of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes. Gregson C, Newel F, Leo PJ, Clark GR, Paternoster L, Mhairi M, Forgetta V, Morris JA, Ge B, Bao X, Bassett JHD, Williams GR, Youlten SE, Croucher PI, Davey Smith G, Evans DM, Kemp JP, Brown MA, Tobias JH, Duncan EL. Bone (2018).

12. FAM210A is a Novel Determinant of Bone and Muscle Structure and Strength. Tanaka K, Xue Y, Nguyen-Yamamoto L, Morris JA, Kanazawa I, Sugimoto T, Wing SS, Richards JB, Goltzman D. Proceedings of the National Academy of Sciences of the USA (2018).

11. Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis. Kemp JP*, Morris JA*, Medina-Gomez C*, Forgetta V, Warrington NM, Youlten SE, Zheng J, Gregson CL, Grundberg E, Trajanoska K, Logan JG, Pollard AS, Sparks PC, Ghirardello EJ, Allen R, Leitch VD, Butterfield NC, Komla-Ebri DSK, Adoum A-T, Curry KF, White JK, Kussy F, Greenlaw K, Xu CJ, Harvey NC, Cooper C, Adams DJ, Greenwood CMT, Maurano MT, Kaptoge S, Rivadeneira F, Tobias JH, Croucher PI, Ackert-Bicknell CL, Bassett JHD, Williams GR, Richards JB, Evans DM. Nature Genetics (2017).

10. Epigenome-wide association of DNA methylation in whole blood with bone mineral density. Morris JA*, Tsai P-C*, Joehanes R*, Zheng J*, Trajanoska K*, Soerensen M*, Forgetta V, Castillo-Fernandez JE, Frost M, Spector TD, Christensen K, Christiansen L, Rivadeneira F, Tobias JH, Evans DM, Kiel DP, Hsu Y-H, Richards JB, Bell JT. Journal for Bone and Mineral Research (2017).

9. Metabolomic Pathways to Osteoporosis in Middle-Aged Women: A Genome-Metabolome-Wide Mendelian Randomization Study. Moayyeri A, Cheung CL, Tan KC, Morris JA, Cerani A, Mohney RP, Richards JB, Hammond C, Spector TD, Menni C. Journal for Bone and Mineral Research (2017).

8. Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. Willems SM, Wright DJ, Day FR, Trajanoska K, Joshi PK, Morris JA, Matteini AM, Garton FC, Grarup N, Oskolkov N, Thalamuthu A, Mangino M, Liu J, Demirkan A, Lek M, Xu L, Wang G, Oldmeadow C, Gaulton KJ, Lotta LA, Miyamoto-Mikami E, Rivas MA, White T, Loh P-R, Aadahl M, Amin N, Attia JR, Austin K, Benyamin B, Brage S, Cheng Y-C, Cieszczyk P, Derave W, Eriksson K-F, Eynon N, Linneberg A, Lucia A, Massidda M, Mitchell BD, Miyachi M, Murakami H, Padmanabhan S, Pandey A, Papadimitriou I, Rajpal D, Sale C, Schnurr TM, Sessa F, Shrine N, Tobin MD, Varley I, Wain LV, Wray NR, Lindgren CM, MacArthur DG, Waterworth D, McCarthy MI, Pedersen O, Khaw K-T, Kiel DP, GEFOS Anytype of Fracture Consortium, Pitsiladis Y, Fuku N, Franks PW, North KN, van Duijn CM, Mather KA, Hansen T, Hansson O, Spector T, Murabito JM, Richards JB, Rivadeneira F, Langenberg C, Perry JRB, Wareham NJ, Scott RA. Nature Communications (2017).

7. Using Epigenomic data to inform genome-wide association studies of bone mineral density. Morris JA. Annals of Translational Medicine (2016).

6. A Mendelian randomization study of the effect of type-2 diabetes on bone mineral density. Ahmad OS, Leong A, Miller JA, Morris JA, Forgetta V, Mujamammi M, Richards, JB. Journal for Bone and Mineral Research (2016).

5. Large differences in adiponectin levels have no clear effect on multiple sclerosis risk: A Mendelian randomization study. Devorak J, Mokry LE, Morris JA, Forgetta V, Davey Smith G, Sawcer S, Richards JB. Multiple Sclerosis (2016).

4. Genetically decreased vitamin D and risk of Alzheimer disease. Mokry LE, Ross S, Morris JA, Manousaki D, Forgetta V, Richards JB. Neurology (2016).

3. Genetic drivers of epigenetic and transcriptional variation in human immune cells. Chen L, Ge B, Casale FP, Vasquez L, Kwan T, Garrido-Martín D, Watt S, Yan Y, Kundu K, Ecker S, Datta A, Richardson D, Burden F, Mead D, Mann AL, Fernandez JM, Rowlston S, Wilder SP, Farrow S, Shao X, Lambourne JJ, Redensek A, Albers CA, Amstislavskiy V, Ashford S, Berentsen K, Bomba L, Bourque G, Bujold D, Busche S, Caron M, Chen SH, Cheung W, Delaneau O, Dermitzakis ET, Elding H, Colgiu I, Bagger FO, Flicek P, Habibi E, Iotchkova V, Janssen-Megens E, Kim B, Lehrach H, Lowy E, Mandoli A, Matarese F, Maurano MT, Morris JA, Pancaldi V, Pourfarzad F, Rehnstrom K, Rendon A, Risch T, Sharifi N, Simon MM, Sultan M, Valencia A, Walter K, Wang SY, Frontini M, Antonarakis SE, Clarke L, Yaspo ML, Beck S, Guigo R, Rico D, Martens JH, Ouwehand WH, Kuijpers TW, Paul DS, Stunnenberg HG, Stegle O, Downes K, Pastinen T, Soranzo N. Cell (2016).

2. Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps. Iotchkova V, Huang J, Morris JA, Jain D, Barbieri C, Walter K, Min J, Chen L, Astle W, Cocca M, Deelen P, Elding H, Farmaki A-E, Franklin C, Gaunt T, Hofman A, Jiang T, Kleber M, Luan J, Malerba G, Matchan A, Mead D, Memari Y, Ntalla I, Panoutsopoulou K, Pazoki R, Perry J, Rivadeneira F, Shin S-Y, Southam L, Traglia M, van Dijk D, van Leeuwen E, Zaza G, Zhang W, Amin N, Butterworth A, Chambers J, Dedoussis G, Dehghan A, Franco O, Franke L, Frontini M, Gambaro G, Gasparini P, Isaacs A , Kooner J, Kooperberg C, Langenberg C, März W, Scott R, Swertz M, Toniolo D, Uitterlinden A, van Duijn C, Zeggini E, Maurano M, Lachance G, Timpson N, Frånberg M, Sabater-Lleal M, Sennblad B, Hamsten A, Watkins H, Reiner A, Auer P, Soranzo N. Nature Genetics (2016).

1. A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease. Ahmad OS, Morris JA, Mujammami M, Forgetta V, Leong A, Li R, Turgeon M, Greenwood CMT, Thanassoulis G, Meigs JB, Sladek R, Richards JB. Nature Communications (2015).

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